Flonase Nasal Spray, primarily containing fluticasone propionate, is used to relieve allergy symptoms like sneezing, runny nose, nasal congestion, and itchy or watery eyes. It can be used for both seasonal allergies (hay fever) and year-round allergies (perennial allergic rhinitis). Additionally, it may be used to treat symptoms of nonallergic rhinitis and chronic rhinosinusitis.